STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_1904Hypothetical protein; SWISSPROT Q88NDO; similar to alginate biosynthesis protein algX. (436 aa)    
Predicted Functional Partners:
Dshi_1902
Putative poly(beta-D-mannuronate) O-acetylase; COG: COG1696 - Predicted membrane protein involved in D-alanine export; PFAM: PF03062; Belongs to the membrane-bound acyltransferase family.
  
  
 0.939
Dshi_1903
Putative alginate biosynthesis protein algJ; SWISSPROT Q51393.
  
  
 0.937
Dshi_2669
Hypothetical protein.
  
 
 0.855
Dshi_1901
Hypothetical protein; SWISSPROT Q887Q8: alginate biosynthesis protein algF (precursor). No evidence at protein level and low similarity but the colocation with algC, algA and algD indicates an involvement in alginate biosynthesis; similar to alginate biosynthesis protein algF.
  
    0.759
algA
SWISSPROT P07874: Alginate biosynthesis protein algA; TIGRFAM: TIGR01479 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG: COG0836 - Mannose-1-phosphate guanylyltransferase; PFAM: PF01050, PF00483; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.627
algC
SWISSPROT P26276: Phosphomannomutase/phosphoglucomutase; COG: COG1109 - Phosphomannomutase; PFAM: PF02880, PF02879, PF02878, PF00408; PROSITE: PS00710.
     
 0.544
algD
SWISSPROT P11759: GDP-mannose 6-dehydrogenase; COG: COG1004 - Predicted UDP-glucose 6-dehydrogenase; PROSITE: PS00059; PFAM: PF03721, PF00984, PF03720.
  
  
 0.514
Dshi_1890
Hypothetical protein; PFAM: PF08238; SMART: SM00671; SUPERFAMILY: SSF81901.
  
 
 0.507
Dshi_1898
SWISSPROT Q52463: Glycosyltransferase alg8. Possibly a processive enzyme that polymerizes GDP-mannuronic acid. No evidence at protein level but the colocation with algA and algG indicates an involvement in alginate biosynthesis.
  
  
 0.466
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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