STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2006DK; SWISSPROT O34627: Blue-light photoreceptor; PFAM: PF08447; SMART: SM00086, SM00091; PROSITE: PS50112, PS50113. TD; 1) similar to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); 2) highly conserved LOV consensus region including the photoactive Cys. (139 aa)    
Predicted Functional Partners:
ydaM
TIGRFAM: diguanylate cyclase PFAM: GGDEF domain containing protein; EAL domain protein KEGG: sil:SPO0533 diguanylate cyclase, putative.
  
 
 0.916
Dshi_1644
Histidine kinase; COG: COG4191 - Signal transduction histidine kinase regulating C4-dicarboxylate transport system; SMART: SM0009, SM00448, SM00387, SM00388; PROSITE: PS50110, PS50109; PFAM: PF00072, PF02518, PF00512; SPRINTS: PR00344; SUPERFAMILY: SSF55874.
  
 
 0.907
Dshi_1893
LOV-regulator, Blue-light sensing; Similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator rece [...]
 
0.875
Dshi_3332
Sensor histidine kinase/response regulator; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein KEGG: rde:RD1_0357 hybrid sensory histidine kinase, putative.
 
 
 0.862
Dshi_3065
PFAM: EAL domain protein KEGG: pde:Pden_2025 diguanylate phosphodiesterase, DUF2.
 
 
 0.827
Dshi_2708
Sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein.
 
 
 0.814
Dshi_3346
KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.803
Dshi_2676
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
 0.792
Dshi_0824
Histidine kinase; C-Terminal domain of arcB (aerobic respiration control), no PAS domain (sensor).
 
 
 0.629
Dshi_2005
Putative cytochrome c peroxidase; PFAM: PF03150; Gene3D: G3DSA:1.10.760.10; PROSITE: PS51007.
       0.590
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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