STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2058Short chain dehydrogenase / reductase; COG: COG1028 - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (221 aa)    
Predicted Functional Partners:
Dshi_2057
COG: COG5319 - Uncharacterized protein conserved in bacteria; PFAM: PF06676-Protein of unknown function (DUF1178).
  
    0.847
Dshi_2059
Conserved hypothetical protein; COG: COG0645 - Predicted kinase; similar to adenylyl sulfate kinase.
  
    0.775
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
 
 
 0.715
Dshi_1954
Putative short-chain dehydrogenase; PFAM: PF00106-short chain dehydrogenase; PRINTS: PR00081; COG: COG0300 - Short-chain dehydrogenases of various substrate specificities.
  
   0.587
Dshi_2056
Hypothetical protein; PFAM: PF00293; PRINTS: PR00502; Gene3D: G3DSA:3.90.79.10.
   
  0.582
Dshi_1258
Short-chain dehydrogenase/reductase SDR; Most enzymes of this family are NAD/NADP-dependent oxidoreductases.
  
    0.477
Dshi_0672
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; low swissprot hit to 7-alpha-hydroxysteroid dehydrogenase from Escherichia coli K12; high Ref ZP hit to 7-alpha-hydroxysteroid dehydrogenase, putative [Roseovarius nubinhibens ISM].
  
    0.456
Dshi_0936
Sulfatase; Exported or inner-membrane bound, catalyzes hydrolization of sulfate from organic compounds.
   
 
 0.429
aslA
Arylsulfatase precursor; PFAM: sulfatase KEGG: rde:RD1_0531 arylsulfatase; Aryl-sulfate sulphohydrolase; AS.
   
 
 0.429
Dshi_2055
COG: COG0386 - Glutathione peroxidase; SWISSPROT P99097: Glutathione peroxidase homolog bsaA; PFAM: PF00255; PIR: PIRSF000303; PROSITE: PS00460; PRINTS: PR01011; Gene3D: G3DSA:3.40.30.10; Belongs to the glutathione peroxidase family.
  
 
 0.422
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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