STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysCAspartokinase; SWISSPROT P26512: Aspartokinase; TIGRFAM: TIGR00656 aspartate kinase, monofunctional class, TIGR00657 aspartate kinase; COG: COG0527 - Aspartokinases; Belongs to the aspartokinase family. (412 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.994
Dshi_2273
Swiss-Prot: P29365 - Homoserine dehydrogenase PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding KEGG: sil:SPO1734 homoserine dehydrogenase.
 
 0.979
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.977
argG
TIGRFAM: argininosuccinate synthase PFAM: argininosuccinate synthase KEGG: rde:RD1_0417 argininosuccinate synthase; Citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.896
thrC
Threonine synthase; PLP-dependent enzyme, Reaction: O-phospho-L-homoserine + H2O <=> L-threonine + phosphate.
  
 
 0.880
aspC
Contains Aminotransferase class I and II domain.
 
 0.874
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
 0.857
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
  0.841
pyrB
TIGRFAM: aspartate carbamoyltransferase PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain KEGG: rde:RD1_3427 aspartate carbamoyltransferase; ATCase; Aspartate transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.810
Dshi_2199
Aspartate/glutamate racemase family protein; TIGRFAM: aspartate racemase PFAM: Asp/Glu racemase KEGG: atc:AGR_L_3474 hypothetical protein.
   
 
  0.801
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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