STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Dshi_2208Putative D-alanyl-D-alanine carboxypeptidase/endopeptidase; Swiss-Prot: spP39844, spP45161: Penicillin-binding protein 4 TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C KEGG: sit:TM1040_2259 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase. (495 aa)    
Predicted Functional Partners:
dacC1
Serine-type D-Ala-D-Ala carboxypeptidase; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors, Preferential cleavage: (Ac)2-L-Lys-D-Ala-D-Ala; Belongs to the peptidase S11 family.
   
 
 0.918
Dshi_2095
Conserved hypothetical protein.
  
     0.683
mreC
TIGRFAM: rod shape-determining protein MreC PFAM: Rod shape-determining protein MreC; NCBI conserved domains: PRK10900, cell wall structural complex MreBCD transmembrane component MreC; low swissprot hit to Rod shape-determining protein mreC from Haemophilus influenzae; high Ref ZP hit to rod shape-determining protein MreC [Roseovarius nubinhibens ISM].
  
  
 0.675
Dshi_1928
PFAM: PF04340 - Protein of unknown function, DUF484.
  
     0.663
Dshi_2850
SMART 00382: AAA - ATPases associated with a variety of cellular activities; AAA family.
  
     0.658
Dshi_0589
Conserved hypothetical protein; Unsure GC frame plot, no significant swissprot; no conserved domains detected; high Ref ZP hit to hypothetical protein R2601_11544 [Roseovarius sp. HTCC2601].
  
     0.542
Dshi_2209
Conserved hypothetical protein; Swiss-Prot: spQ9ZE70 COG5006: predicted permease, DMT superfamily PFAM: protein of unknown function DUF6 transmembrane KEGG: jan:Jann_3630 protein of unknown function DUF6, transmembrane; associated with drug/metabolite transport.
       0.523
Dshi_2835
Conserved hypothetical protein; PFAM: Rhomboid family protein KEGG: sit:TM1040_0444 rhomboid-like protein COG0705: Uncharacterized membrane protein (homolog of Drosophila rhomboid); related to rhomboid family protein.
  
     0.520
Dshi_1773
Putative metalloprotease; SWISSPROT P25894: Uncharacterized metalloprotease yggG; PANTHER: OMA1 HOMOLOG, ZINC METALLOPEPTIDASE (PTHR22726); PFAM: PF01435.
  
     0.483
mro
Swiss-Prot: P05149-aldose 1-epimerase [Precursor] PFAM: Aldose 1-epimerase.
  
    0.482
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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