STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2356Conserved hypothetical protein; PFAM: ATPase associated with various cellular activities AAA_5 KEGG: sil:SPO2646 hypothetical protein Swiss-Prot: Q4L6B6-Uncharacterized protein SH1500. (303 aa)    
Predicted Functional Partners:
Dshi_2355
PFAM: VWA containing CoxE family protein KEGG: jan:Jann_1760 VWA containing CoxE-like.
 
     0.897
coxE
Protein containing von Willebrand factor type A (vWA) domain.
 
     0.783
coxL1
Swiss-Prot: P19919-Carbon monoxide dehydrogenase large chain coxL TIGR02416: carbon-monoxide dehydrogenase, large subunit PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
 
   
 0.737
Dshi_2661
PFAM: carbon monoxide dehydrogenase subunit G COG3427: Uncharacterized conserved protein; subunit G.
 
     0.722
Dshi_2658
Swiss-Prot: P19920-Carbon monoxide dehydrogenase medium chain coxM; PFAM: molybdopterin dehydrogenase FAD-binding COG1319: Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs; medium chain.
 
   
 0.714
Dshi_1040
Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; High similarity to predicted Carbon-monoxide dehydrogenase proteins.
 
   
 0.590
coxL3
SWISSPROT P19919: Carbon monoxide dehydrogenase large chain; COG: COG1529 - Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; PFAM: pfam02738, pfam01315.
 
   
 0.569
Dshi_2357
COG1960: Acyl-CoA dehydrogenases PFAM: Acyl-CoA dehydrogenase.
       0.527
Dshi_2350
Swiss-Prot: Q58296-Putative molybdopterin biosynthesis protein MJ0886 PFAM: molybdopterin binding domain COG0303: Molybdopterin biosynthesis enzyme.
 
     0.478
coxL2
Aerobic-type carbon monoxide dehydrogenase, large subunit, part of heterotrimer coxLMS.
 
   
 0.466
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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