STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2521Transcriptional regulator; Swiss-Prot: P0ACJ8-Catabolite gene activator crp PFAM: cyclic nucleotide-binding SMART: regulatory protein Crp KEGG: sil:SPO1615 cyclic nucleotide-binding protein; Crp/Fnr family. (225 aa)    
Predicted Functional Partners:
Dshi_2520
KEGG: rde:RD1_0788 hypothetical protein.
 
     0.767
Dshi_0843
Thioesterase superfamily protein.
   
    0.682
Dshi_2522
Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.601
fixK
PFAM: cyclic nucleotide-binding; regulatory protein Crp, NCBI conserved domains: PRK09391, fixK, transcriptional regulator FixK; high swissprot hit to Transcriptional activator protein fnrL from Rhodobacter sphaeroides 2.4.1; high Ref ZP hit to transcriptional activator protein FnrL [Roseovarius sp. 217]; Crp/Fnr family; alternative gene name: fnrL.
  
   
 0.574
Dshi_3189
Transcriptional regulator; PFAM: cyclic nucleotide-binding KEGG: sil:SPOA0323 cyclic nucleotide-binding protein; similar to DnrD.
  
   
 0.570
Dshi_2518
Conserved hypothetical protein; Swiss-Prot: Q87AD3-UPF0394 membrane protein PD_1893 PFAM: protein of unknown function DUF395 YeeE/YedE KEGG: sit:TM1040_3646 protein of unknown function DUF395, YeeE/YedE.
  
    0.534
Dshi_2519
Conserved hypothetical protein; PFAM: protein of unknown function DUF395 YeeE/YedE KEGG: jan:Jann_2818 protein of unknown function DUF395, YeeE/YedE.
       0.526
Dshi_0447
PFAM: cyclic nucleotide-binding SMART: regulatory protein Crp; low swissprot hit to Transcriptional activatory protein aadR from Rhodopseudomonas palustris and middle Ref ZP hit to transcriptional regulator, Crp/Fnr family protein from Roseobacter sp. AzwK-3b; Crp/Fnr family.
      
 0.510
Dshi_3270
Conserved hypothetical protein.
      
 0.510
Dshi_2517
Hypothetical protein; Swiss-Prot: Q8UAA9-Beta-lactamase hydrolase-like protein PFAM: beta-lactamase domain protein KEGG: rde:RD1_0785 metallo-beta-lactamase family protein; related to beta-lactamase hydrolase-like protein.
       0.483
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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