STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2546Dehydrogenase; Swiss-Prot: O34736-Uncharacterized oxidoreductase yjmC PFAM: Malate/L-lactate dehydrogenase KEGG: tth:TT_P0035 dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (351 aa)    
Predicted Functional Partners:
Dshi_2544
ABC transporter; Swiss-Prot: Q57855-Uncharacterized ABC transporter ATP-binding protein MJ0412 PFAM: ABC transporter related SMART: AAA ATPase KEGG: rsh:Rsph17029_3905 ABC transporter related; ATP-binding protein.
       0.778
Dshi_2545
Swiss-Prot: P40401-Putative aliphatic sulfonates transport permease protein PFAM: binding-protein-dependent transport systems inner membrane component; inner membrane component.
       0.778
Dshi_2543
Putative binding protein; Swiss-Prot: P40400-Putative aliphatic sulfonates-binding protein [Precursor] PFAM: NMT1/THI5 like domain protein.
       0.774
rDP
PFAM: peptidase M19 renal dipeptidase; NCBI conserved domains: rDP-like; low swissprot hit to Dipeptidase 1 precursor from Oryctolagus cuniculus; high Ref ZP hit to peptidase M19, renal dipeptidase [Roseovarius sp. TM1035].
  
    0.704
Dshi_2542
Conserved hypothetical protein; Swiss-Prot: P76004-Uncharacterized protein ycgM PFAM: fumarylacetoacetate (FAA) hydrolase KEGG: bxe:Bxe_A3618 putative hydrolase; related to fumarylacetoacetate (FAA) hydrolase.
  
    0.675
Dshi_1426
Hydro-lyase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.495
Dshi_2541
Transcriptional regulator; Swiss-Prot: P0ACL7- Putative L-lactate dehydrogenase operon regulatory protein PFAM: regulatory protein GntR HTH; GntR domain protein KEGG: rle:RL4574 putative GntR family transcriptional regulator; gntR family.
  
    0.461
gap1
SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.442
Dshi_1254
Glyceraldehyde-3-phosphate dehydrogenase; Tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis; type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
      
 0.439
gap2
SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
      
 0.439
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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