STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobT1Swiss-Prot: P29934-Aerobic cobaltochelatase subunit cobT TIGR01651: cobaltochelatase, CobT subunit PFAM: Cobalt chelatase CobT subunit SMART: von Willebrand factor type A. (624 aa)    
Predicted Functional Partners:
cobS2
Swiss-Prot: P29933-Aerobic cobaltochelatase subunit cobS TIGRFAM: cobalt chelatase, pCobS small subunit PFAM: ATPase associated with various cellular activities AAA_5.
 
 
 0.992
cobN
Cobaltochelatase; KEGG: bov:BOV_1269 cobaltochelatase, CobN subunit TIGRFAM: cobaltochelatase, CobN subunit PFAM: CobN/magnesium chelatase; swissprot: high similarity to aerobic cobaltochelatase subunit cobN from Pseudomonas denitrificans; gene arangement from Dshi_0157 to Dshi_0166 Vit B12 synthesis.
     
 0.917
cobA2
cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
     
 0.901
Dshi_0218
TIGRFAM: ATP--cobalamin adenosyltransferase PFAM: cobalamin adenosyltransferase KEGG: rde:RD1_1389 cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family.
    
  0.901
cobB
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
     
  0.900
Dshi_1202
Contains DnaJ-Domain, wich mediats interaction with DnaK in heat shock proteins.
 
     0.716
Dshi_2616
PFAM: GcrA cell cycle regulator KEGG: jan:Jann_1020 GcrA cell cycle regulator.
  
     0.683
holC
DNA polymerase III chi subunit HolC; Neccesary for a functional clamp-loading complex to form.
  
     0.634
Dshi_0255
PFAM: protein of unknown function DUF1013 KEGG: rde:RD1_1043 hypothetical protein.
  
     0.628
atpX
ATP synthase F0; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).
  
     0.609
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: low (24%) [HD]