Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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gshBSwiss-Prot: P04425-Glutathione synthetase TIGRFAM: glutathione synthetase PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family. (315 aa)    
Predicted Functional Partners:
gst1
PFAM: Glutathione S-transferase domain KEGG: rsq:Rsph17025_2783 glutathione S-transferase, N-terminal domain.
 
  
 0.951
gor
Swiss-Prot: P06715-Glutathione reductase PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.
  
  
 0.948
gsh
Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
 0.945
pepA1
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.944
Dshi_2055
COG: COG0386 - Glutathione peroxidase; SWISSPROT P99097: Glutathione peroxidase homolog bsaA; PFAM: PF00255; PIR: PIRSF000303; PROSITE: PS00460; PRINTS: PR01011; Gene3D: G3DSA:3.40.30.10; Belongs to the glutathione peroxidase family.
    
 0.938
pepA2
PFAM: peptidase M17 leucyl aminopeptidase domain protein KEGG: sil:SPO3717 cytosol aminopeptidase family protein; (LAP) (Leucyl aminopeptidase).
   
 
 0.925
ggt1
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase KEGG: sit:TM1040_0064 gamma-glutamyltransferase, good swissprot hit to Gamma-glutamyltranspeptidase precursor from Bacillus subtilis.
    
 0.917
ggt2
TIGRFAM: gamma-glutamyltransferase PFAM: gamma-glutamyltranspeptidase; NCBI conserved domains: ggT; high swissprot hit to Gamma-glutamyltranspeptidase precursor from Escherichia coli K12; high Ref YP hit to Gamma-glutamyltransferase [Jannaschia sp. CCS1].
    
 0.917
Dshi_1749
Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
    
 0.917
pepN
Involved in the degradation of intracellular peptides generated by protein breakdown during normal growth or in response to nutrient starvation, Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action).
    
 0.914
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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