STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rluESWISSPROT P75966: Ribosomal large subunit pseudouridine synthase E; TIGRFAM: TIGR00093 pseudouridine synthase family; COG: COG1187 - 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; PFAM: PF00849 - RNA pseudouridylate synthase; PROSITE: PS01149; Belongs to the pseudouridine synthase RsuA family. (178 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase EC:2.7.4.14 catalyses the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5-diphosphate (dCDP) in the presence of ATP or GTP, Reaction: ATP + (d)CMP <=> ADP + (d)CDP.
 
  
 0.770
Dshi_0832
Conserved hypothetical protein; Conserved in Rhodobacteraceae.
   
    0.701
engA
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.680
xthA
TIGRFAM: exodeoxyribonuclease III Xth PFAM: Endonuclease/exonuclease/phosphatase KEGG: sit:TM1040_0053 exodeoxyribonuclease III, best swissprot hit to Exodeoxyribonuclease III (Exonuclease III) from Escherichia coli.
  
    0.623
Dshi_1886
TIGRFAM: TIGR00195 exodeoxyribonuclease III, TIGR00633 exodeoxyribonuclease III (xth); COG: COG0708 - Exonuclease III; PFAM: PF03372-Endonuclease/Exonuclease/phosphatase family; PROSITE: PS00726; xthA.
  
    0.623
Dshi_2720
PFAM: Endonuclease/exonuclease/phosphatase.
  
    0.623
Dshi_1724
Putative segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.617
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.588
pheT
KEGG: rde:RD1_1013 phenylalanyl-tRNA synthetase, beta subunit TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
     
 0.501
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.