STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_2925TIGRFAM: TIGR01459 HAD-superfamily class IIA hydrolase, TIGR01459 TIGR01460 Haloacid Dehalogenase Superfamily Class (subfamily) IIA; COG: COG0647 - Predicted sugar phosphatases of the HAD superfamily; PFAM: PF00702. (290 aa)    
Predicted Functional Partners:
Dshi_3429
PFAM: HD domain KEGG: sit:TM1040_2836 metal dependent phosphohydrolase.
 
  
 0.745
Dshi_2926
Putative MaoC-like dehydratase; SWISSPROT P77455: Protein maoC; PFAM: PF01575; COG: COG2030 - Acyl dehydratase.
  
    0.610
Dshi_2775
Swiss-Prot:Q52911-Uncharacterized HTH-type transcriptional regulator R00410 PFAM: helix-turn-helix domain protein COG1396: Predicted transcriptional regulators SM00530: Helix-turn-helix XRE-family like proteins; XRE family.
  
    0.554
ribF
SWISSPROT P0AG40: Riboflavin biosynthesis protein; TIGRFAM: TIGR00083 riboflavin kinase/FMN adenylyltransferase; COG: COG0196 - FAD synthase; PFAM: PF06574; Gene3D: G3DSA:3.40.50.620; Belongs to the ribF family.
  
    0.544
ppaC
Pyrophosphate phospho-hydrolase; SWISSPROT Q9RRB7: Probable manganese-dependent inorganic pyrophosphatase; COG: COG1227 - Inorganic pyrophosphatase/exopolyphosphatase; PFAM: PF01368, PF02833.
  
    0.527
Dshi_2928
Conserved hypothetical protein UPF0153 family; COG: COG2983 - Uncharacterized conserved protein; PFAM: PF03692 - Uncharacterized protein family (UPF0153); Belongs to the UPF0260 family.
       0.522
hisS
TIGRFAM: TIGR00442 histidyl-tRNA synthetase; COG: COG0124 - Histidyl-tRNA synthetase; PFAM: PF00587, PF03129; PROSITE: PS50862.
 
    0.522
Dshi_3418
PFAM: HemY domain protein.
  
    0.463
Dshi_2938
Conserved hypohtetical protein.
 
     0.462
cysC
Putative bifunctional SAT/APS kinase: sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate.
  
   0.456
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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