Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Dshi_3205TIGRFAM: Hydroxyisourate hydrolase PFAM: Transthyretin KEGG: rde:RD1_4150 hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (117 aa)    
Predicted Functional Partners:
Dshi_3204
PFAM: polysaccharide deacetylase; pfam09349, OHCU_decarbox, OHCU decarboxylase. KEGG: jan:Jann_2608 polysaccharide deacetylase.
  
 0.964
Dshi_2684
Swiss-Prot: Q92UG5-Putative transthyretin-like protein RB1166 TIGRFAM: Hydroxyisourate hydrolase PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
  
  
 
0.903
Dshi_3207
PFAM: protein of unknown function DUF989 KEGG: rde:RD1_4148 hypothetical protein.
 
  
 0.813
allA
Ureidoglycolatehydrolase; PFAM: Ureidoglycolate hydrolase KEGG: rsh:Rsph17029_0204 ureidoglycolate hydrolase.
 
    0.770
xdhA
SWISSPROT Q46799: Xanthine dehydrogenase molybdenum-binding subunit; TIGRFAM: TIGR02965 xanthine dehydrogenase, molybdopterin binding subunit; COG: COG4631 - Xanthine dehydrogenase, molybdopterin-binding subunit B.
 
  
 0.768
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.735
xghB
Putative xanthine dehydrogenase; PFAM: PF00111, PF00941, PF01799, PF03450; TIGRFAM: TIGR02963 xanthine dehydrogenase, small subunit; COG: COG4630 - Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A; iron-sulfur-binding subunit and FAD-binding subunit.
 
     0.717
uraA
TIGRFAM: uracil-xanthine permease PFAM: Xanthine/uracil/vitamin C permease KEGG: rde:RD1_4153 xanthine/uracil permease, putative,10xTHM; Uracil transporter.
 
  
 0.665
Dshi_1056
Polysaccharide deacetylase.
 
    0.657
yedZ
Putative sulfite oxidase subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subuni [...]
   
    0.623
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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