STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_3206PFAM: regulatory protein LysR; LysR substrate-binding; HTH_1 pfam00126 Bacterial regulatory helix-turn-helix protein, lysR family KEGG: rde:RD1_4149 transcriptional regulator, LysR family, putative; LysR family. (327 aa)    
Predicted Functional Partners:
Dshi_3207
PFAM: protein of unknown function DUF989 KEGG: rde:RD1_4148 hypothetical protein.
 
     0.647
uraA
TIGRFAM: uracil-xanthine permease PFAM: Xanthine/uracil/vitamin C permease KEGG: rde:RD1_4153 xanthine/uracil permease, putative,10xTHM; Uracil transporter.
  
     0.580
Dshi_1431
Transcriptional regulator; Contains substrate binding domain, putative homotetramer; LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.518
Dshi_0576
PFAM: regulatory protein LysR; LysR substrate-binding; low swissprot hit to Uncharacterized HTH-type transcriptional regulator ydcI from Escherichia coli K12; middle Ref ZP hit to transcriptional regulator, LysR family protein [Roseobacter sp. AzwK-3b]; LysR family.
  
     0.440
Dshi_2347
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding COG0583: transcriptional regulator Swiss-Prot: P55700-nodulation protein D 2 (Represses the expression of the nodABCIJ-nolO-noeI operon).
  
     0.432
Dshi_0889
Contains N-terminal domain of alanine racemase, C-terminal domain missing.
  
     0.422
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.405
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.