Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_3207PFAM: protein of unknown function DUF989 KEGG: rde:RD1_4148 hypothetical protein. (410 aa)    
Predicted Functional Partners:
Dshi_3204
PFAM: polysaccharide deacetylase; pfam09349, OHCU_decarbox, OHCU decarboxylase. KEGG: jan:Jann_2608 polysaccharide deacetylase.
 
    0.891
allA
Ureidoglycolatehydrolase; PFAM: Ureidoglycolate hydrolase KEGG: rsh:Rsph17029_0204 ureidoglycolate hydrolase.
 
    0.867
Dshi_3205
TIGRFAM: Hydroxyisourate hydrolase PFAM: Transthyretin KEGG: rde:RD1_4150 hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
  
 0.813
Dshi_2684
Swiss-Prot: Q92UG5-Putative transthyretin-like protein RB1166 TIGRFAM: Hydroxyisourate hydrolase PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
  
 0.809
xdhA
SWISSPROT Q46799: Xanthine dehydrogenase molybdenum-binding subunit; TIGRFAM: TIGR02965 xanthine dehydrogenase, molybdopterin binding subunit; COG: COG4631 - Xanthine dehydrogenase, molybdopterin-binding subunit B.
 
     0.765
xghB
Putative xanthine dehydrogenase; PFAM: PF00111, PF00941, PF01799, PF03450; TIGRFAM: TIGR02963 xanthine dehydrogenase, small subunit; COG: COG4630 - Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A; iron-sulfur-binding subunit and FAD-binding subunit.
 
     0.754
xdhC
TIGRFAM: TIGR02964 xanthine dehydrogenase accessory protein XdhC; PFAM: PF02625; COG: COG1975 - Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.
 
    0.691
Dshi_3206
PFAM: regulatory protein LysR; LysR substrate-binding; HTH_1 pfam00126 Bacterial regulatory helix-turn-helix protein, lysR family KEGG: rde:RD1_4149 transcriptional regulator, LysR family, putative; LysR family.
 
     0.647
Dshi_3200
PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein KEGG: jan:Jann_2601 protein of unknown function DUF861, cupin_3.
 
     0.581
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
     0.579
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.