STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ymdCPFAM: phospholipase D/Transphosphatidylase KEGG: bpe:BP3092 putative phospholipase D protein. (529 aa)    
Predicted Functional Partners:
Dshi_0421
PFAM: phospholipase D/Transphosphatidylase KEGG: pmy:Pmen_2055 phospholipase D/transphosphatidylase; high swissprot hit to Uncharacterized protein ymdC from Escherichia coli K12 and high Ref EDP hit to phospholipase D/Transphosphatidylase from Oceanibulbus indolifex HEL-45; NCBI conserved domains: PLDc.
  
  
 
0.917
Dshi_1578
Putative phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
     
 0.912
Dshi_1516
Conserved hypothetical protein; PFAM: PF01592, COG: COG0822 - NifU homolog involved in Fe-S cluster formation; related to NIFU.
   
 
 0.740
ispDF
Bifunctional enzyme ispD/ispF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
     
 0.536
Dshi_0420
PFAM: Endonuclease/exonuclease/phosphatase KEGG: sil:SPO2482 endonuclease/exonuclease/phosphatase family protein; no significant swissprot; good Ref EDP hit to metal-dependent hydrolase from Oceanibulbus indolifex HEL-45, NCBI conserved domains: elsH, Metal-dependent hydrolase.
 
    0.527
Dshi_3209
Hypothetical protein.
       0.519
Dshi_1564
Hypothetical protein; PROSITE: PS51257, PFAM: pfam04366, COG: COG2930 - Uncharacterized conserved protein.
 
    0.495
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.491
kefC
Potassium efflux system protein; Glutathione regulated, K+/H+ antiporter, NAD-binding domain; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
  
 0.438
aslA
Arylsulfatase precursor; PFAM: sulfatase KEGG: rde:RD1_0531 arylsulfatase; Aryl-sulfate sulphohydrolase; AS.
 
  
 0.416
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.