node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dshi_3459 | Dshi_3461 | Dshi_3459 | Dshi_3461 | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | 0.778 |
Dshi_3459 | ham1 | Dshi_3459 | Dshi_3462 | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.809 |
Dshi_3459 | hemN3 | Dshi_3459 | Dshi_3460 | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.809 |
Dshi_3459 | rph | Dshi_3459 | Dshi_3463 | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.809 |
Dshi_3461 | Dshi_3459 | Dshi_3461 | Dshi_3459 | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | 0.778 |
Dshi_3461 | ham1 | Dshi_3461 | Dshi_3462 | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.956 |
Dshi_3461 | hemN3 | Dshi_3461 | Dshi_3460 | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.792 |
Dshi_3461 | rph | Dshi_3461 | Dshi_3463 | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.841 |
Dshi_3589 | rnr | Dshi_3589 | Dshi_0015 | PFAM: 3-5 exonuclease. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.910 |
Dshi_3589 | rph | Dshi_3589 | Dshi_3463 | PFAM: 3-5 exonuclease. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.930 |
Dshi_3589 | rpsA | Dshi_3589 | Dshi_1025 | PFAM: 3-5 exonuclease. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.897 |
Dshi_3589 | rpsD | Dshi_3589 | Dshi_2948 | PFAM: 3-5 exonuclease. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.895 |
dnaG | rph | Dshi_2262 | Dshi_3463 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.822 |
ham1 | Dshi_3459 | Dshi_3462 | Dshi_3459 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | 0.809 |
ham1 | Dshi_3461 | Dshi_3462 | Dshi_3461 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | 0.956 |
ham1 | hemN3 | Dshi_3462 | Dshi_3460 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.953 |
ham1 | rph | Dshi_3462 | Dshi_3463 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.992 |
hemN3 | Dshi_3459 | Dshi_3460 | Dshi_3459 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: protein of unknown function DUF454 KEGG: rsh:Rsph17029_2886 protein of unknown function DUF454. | 0.809 |
hemN3 | Dshi_3461 | Dshi_3460 | Dshi_3461 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: Endoribonuclease L-PSP KEGG: rsp:RSP_1223 putative translation initiation inhibitor, YjgF family / putative endoribonuclease L-PSP. | 0.792 |
hemN3 | ham1 | Dshi_3460 | Dshi_3462 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.953 |