STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGAM01_v207714Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (322 aa)    
Predicted Functional Partners:
TGAM01_v207327
Uncharacterized protein.
  
  
 0.804
TGAM01_v207571
Uncharacterized protein.
  
  
 0.792
TGAM01_v203017
PfkB domain-containing protein.
     
 0.697
TGAM01_v201773
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
     
 0.686
TGAM01_v209757
C2H2-type domain-containing protein.
     
 0.674
TGAM01_v201772
Riboflavin biosynthesis protein RibD domain-containing protein.
     
 0.674
TGAM01_v205423
PfkB domain-containing protein.
     
 0.670
TGAM01_v207686
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.529
TGAM01_v210636
Glyceraldehyde 3-phosphate dehydrogenase.
   
  
 0.528
TGAM01_v205410
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.528
Your Current Organism:
Trichoderma gamsii
NCBI taxonomy Id: 398673
Other names: BPI 872183, C.P.K. 2074, CBS 120075, CPK 2074, FMR 12636, G.J.S. 06-09, GJS 06-09, T. gamsii, Trichoderma gamsii Samuels & Druzhinina, 2006, Trichoderma sp. GJS 04-09
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