Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TGAM01_v207707Aminotran_5 domain-containing protein. (466 aa)    
Predicted Functional Partners:
TGAM01_v208930
Uncharacterized protein.
     
 0.971
TGAM01_v208068
Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 0.971
TGAM01_v205940
Aminotransferase.
     
  0.925
TGAM01_v201490
Uncharacterized protein.
   
 0.909
TGAM01_v202620
Methyltransf_33 domain-containing protein.
     
 0.879
uba4
Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
 0.847
TGAM01_v210229
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.844
TGAM01_v210217
Uncharacterized protein.
  
 0.844
TGAM01_v208686
Uncharacterized protein.
   
 0.836
TGAM01_v207265
Fe-S protein assembly co-chaperone HscB.
  
 0.811
Your Current Organism:
Trichoderma gamsii
NCBI taxonomy Id: 398673
Other names: BPI 872183, C.P.K. 2074, CBS 120075, CPK 2074, FMR 12636, G.J.S. 06-09, GJS 06-09, T. gamsii, Trichoderma gamsii Samuels & Druzhinina, 2006, Trichoderma sp. GJS 04-09
Server load: low (14%) [HD]