Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
whiB-2WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (84 aa)    
Predicted Functional Partners:
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.916
ORB70223.1
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.779
ORB64412.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
ORB71560.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.771
ORB62157.1
Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.770
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.757
nucS
Endonuclease; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.736
ORB69121.1
Cytochrome; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
ORB69823.1
Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.714
ORB66456.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.695
Your Current Organism:
Mycobacterium shinjukuense
NCBI taxonomy Id: 398694
Other names: CCUG 53584, DSM 45663, JCM 14233, M. shinjukuense, Mycobacterium shinjukuense Saito et al. 2011, Mycobacterium sp. GTC2738, strain GTC 2738
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