STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ48147.1Carbohydrate kinase, PfkB family protein; COG0524 Sugar kinases, ribokinase family. (307 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.799
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.779
EAQ48146.1
COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase.
  
   0.720
EAQ50047.1
COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase.
  
 
 0.663
guaB
Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.641
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.609
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide(ProFAR) isomerase; COG2827 Predicted endonuclease containing a URI domain.
  
    0.558
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.544
EAQ48148.1
Ribonuclease H-related protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
       0.536
EAQ50312.1
COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.523
Your Current Organism:
Leeuwenhoekiella blandensis
NCBI taxonomy Id: 398720
Other names: Flavobacterium sp. MED217, L. blandensis MED217, Leeuwenhoekiella blandensis MED217
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