node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ48169.1 | EAQ48910.1 | MED217_00185 | MED217_10187 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | COG0067 Glutamate synthase domain 1. | 0.902 |
EAQ48169.1 | EAQ49222.1 | MED217_00185 | MED217_07451 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.673 |
EAQ48169.1 | EAQ49299.1 | MED217_00185 | MED217_07836 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.703 |
EAQ48169.1 | EAQ50185.1 | MED217_00185 | MED217_04117 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.673 |
EAQ48169.1 | EAQ50628.1 | MED217_00185 | MED217_06332 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.691 |
EAQ48169.1 | EAQ51138.1 | MED217_00185 | MED217_16385 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | COG0281 Malic enzyme. | 0.738 |
EAQ48169.1 | EAQ51351.1 | MED217_00185 | MED217_17450 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.685 |
EAQ48169.1 | fmt | MED217_00185 | MED217_06387 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.896 |
EAQ48169.1 | gcvP | MED217_00185 | MED217_03775 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.679 |
EAQ48169.1 | pckA | MED217_00185 | MED217_01085 | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.668 |
EAQ48910.1 | EAQ48169.1 | MED217_10187 | MED217_00185 | COG0067 Glutamate synthase domain 1. | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.902 |
EAQ48910.1 | EAQ49299.1 | MED217_10187 | MED217_07836 | COG0067 Glutamate synthase domain 1. | COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.588 |
EAQ48910.1 | EAQ50185.1 | MED217_10187 | MED217_04117 | COG0067 Glutamate synthase domain 1. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.947 |
EAQ48910.1 | EAQ50628.1 | MED217_10187 | MED217_06332 | COG0067 Glutamate synthase domain 1. | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.919 |
EAQ48910.1 | EAQ51138.1 | MED217_10187 | MED217_16385 | COG0067 Glutamate synthase domain 1. | COG0281 Malic enzyme. | 0.624 |
EAQ48910.1 | EAQ51351.1 | MED217_10187 | MED217_17450 | COG0067 Glutamate synthase domain 1. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.608 |
EAQ48910.1 | gcvP | MED217_10187 | MED217_03775 | COG0067 Glutamate synthase domain 1. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.953 |
EAQ48910.1 | pckA | MED217_10187 | MED217_01085 | COG0067 Glutamate synthase domain 1. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.921 |
EAQ49222.1 | EAQ48169.1 | MED217_07451 | MED217_00185 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Probable piperideine-6-carboxylate dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.673 |
EAQ49222.1 | EAQ49299.1 | MED217_07451 | MED217_07836 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.946 |