| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ47790.1 | cmk | MED217_08125 | MED217_07276 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | COG0283 Cytidylate kinase. | 0.469 |
| EAQ47790.1 | coaX | MED217_08125 | MED217_03340 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.920 |
| EAQ47790.1 | panB | MED217_08125 | MED217_10924 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.415 |
| EAQ47790.1 | panC | MED217_08125 | MED217_00665 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.924 |
| EAQ47790.1 | panD | MED217_08125 | MED217_00660 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.414 |
| EAQ48263.1 | panC | MED217_00655 | MED217_00665 | Hypothetical protein; COG0392 Predicted integral membrane protein. | Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.786 |
| EAQ48263.1 | panD | MED217_00655 | MED217_00660 | Hypothetical protein; COG0392 Predicted integral membrane protein. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.821 |
| EAQ48336.1 | panB | MED217_01020 | MED217_10924 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.953 |
| EAQ48336.1 | panC | MED217_01020 | MED217_00665 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.953 |
| EAQ48732.1 | panB | MED217_09295 | MED217_10924 | Hypothetical protein. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.800 |
| EAQ48732.1 | panC | MED217_09295 | MED217_00665 | Hypothetical protein. | Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.822 |
| EAQ48732.1 | panD | MED217_09295 | MED217_00660 | Hypothetical protein. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.573 |
| EAQ50062.1 | EAQ50628.1 | MED217_02890 | MED217_06332 | Decarboxylase, pyridoxal-dependent; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.705 |
| EAQ50062.1 | panC | MED217_02890 | MED217_00665 | Decarboxylase, pyridoxal-dependent; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. | Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.886 |
| EAQ50062.1 | panD | MED217_02890 | MED217_00660 | Decarboxylase, pyridoxal-dependent; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.828 |
| EAQ50628.1 | EAQ50062.1 | MED217_06332 | MED217_02890 | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Decarboxylase, pyridoxal-dependent; COG0076 Glutamate decarboxylase and related PLP-dependent proteins. | 0.705 |
| EAQ50628.1 | panC | MED217_06332 | MED217_00665 | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.882 |
| EAQ50628.1 | panD | MED217_06332 | MED217_00660 | COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.896 |
| cmk | EAQ47790.1 | MED217_07276 | MED217_08125 | COG0283 Cytidylate kinase. | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.469 |
| cmk | coaX | MED217_07276 | MED217_03340 | COG0283 Cytidylate kinase. | Putative regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.602 |