STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)    
Predicted Functional Partners:
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.960
EAQ49982.1
COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes.
    
 0.959
EAQ50321.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.902
fbp
COG0158 Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
    
 0.870
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
   
  
 0.868
EAQ48154.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.827
EAQ49980.1
Carboxylesterase (est-1); COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.799
EAQ49983.1
COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase.
  
  
 0.791
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.782
EAQ49977.1
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.777
Your Current Organism:
Leeuwenhoekiella blandensis
NCBI taxonomy Id: 398720
Other names: Flavobacterium sp. MED217, L. blandensis MED217, Leeuwenhoekiella blandensis MED217
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