| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ48154.1 | EAQ48942.1 | MED217_00110 | MED217_10347 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | 0.950 |
| EAQ48154.1 | EAQ50321.1 | MED217_00110 | MED217_04797 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.954 |
| EAQ48154.1 | eno | MED217_00110 | MED217_04112 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.994 |
| EAQ48154.1 | pckA | MED217_00110 | MED217_01085 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.904 |
| EAQ48154.1 | pgi | MED217_00110 | MED217_00585 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.986 |
| EAQ48154.1 | pgk | MED217_00110 | MED217_18376 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.914 |
| EAQ48154.1 | rplD | MED217_00110 | MED217_03967 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.932 |
| EAQ48154.1 | tal | MED217_00110 | MED217_06042 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.919 |
| EAQ48154.1 | tpiA | MED217_00110 | MED217_04447 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.927 |
| EAQ48942.1 | EAQ48154.1 | MED217_10347 | MED217_00110 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.950 |
| EAQ48942.1 | EAQ50321.1 | MED217_10347 | MED217_04797 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.909 |
| EAQ48942.1 | eno | MED217_10347 | MED217_04112 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.951 |
| EAQ48942.1 | gpmI | MED217_10347 | MED217_14920 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.422 |
| EAQ48942.1 | pckA | MED217_10347 | MED217_01085 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.904 |
| EAQ48942.1 | pgi | MED217_10347 | MED217_00585 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.909 |
| EAQ48942.1 | pgk | MED217_10347 | MED217_18376 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.561 |
| EAQ48942.1 | tal | MED217_10347 | MED217_06042 | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.904 |
| EAQ50321.1 | EAQ48154.1 | MED217_04797 | MED217_00110 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.954 |
| EAQ50321.1 | EAQ48942.1 | MED217_04797 | MED217_10347 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Phosphoenolpyruvate synthase (ppsA); COG1196 Chromosome segregation ATPases. | 0.909 |
| EAQ50321.1 | eno | MED217_04797 | MED217_04112 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.981 |