node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ49231.1 | trmH | MED217_07496 | MED217_07491 | Hypothetical protein. | spoU protein; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.773 |
EAQ50181.1 | rplC | MED217_04097 | MED217_03962 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.999 |
EAQ50181.1 | rplK | MED217_04097 | MED217_14075 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
EAQ50181.1 | rplM | MED217_04097 | MED217_16670 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
EAQ50181.1 | rplO | MED217_04097 | MED217_04057 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | Putative 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
EAQ50181.1 | rplU | MED217_04097 | MED217_00835 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.999 |
EAQ50181.1 | rplX | MED217_04097 | MED217_04017 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.999 |
EAQ50181.1 | rsfS | MED217_04097 | MED217_15335 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.999 |
EAQ50181.1 | trmH | MED217_04097 | MED217_07491 | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | spoU protein; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.790 |
recG | trmH | MED217_06072 | MED217_07491 | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | spoU protein; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.819 |
rplC | EAQ50181.1 | MED217_03962 | MED217_04097 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 0.999 |
rplC | rplK | MED217_03962 | MED217_14075 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
rplC | rplM | MED217_03962 | MED217_16670 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
rplC | rplO | MED217_03962 | MED217_04057 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Putative 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
rplC | rplU | MED217_03962 | MED217_00835 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.999 |
rplC | rplX | MED217_03962 | MED217_04017 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.999 |
rplC | rsfS | MED217_03962 | MED217_15335 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.999 |
rplC | trmH | MED217_03962 | MED217_07491 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | spoU protein; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.770 |
rplK | EAQ50181.1 | MED217_14075 | MED217_04097 | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family. | 0.999 |
rplK | rplC | MED217_14075 | MED217_03962 | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.999 |