node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ49347.1 | EAQ49348.1 | MED217_08076 | MED217_08081 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | 0.980 |
EAQ49347.1 | EAQ49522.1 | MED217_08076 | MED217_11724 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Competence-damage inducible protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.692 |
EAQ49347.1 | EAQ51076.1 | MED217_08076 | MED217_16075 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.637 |
EAQ49347.1 | adk | MED217_08076 | MED217_03820 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.668 |
EAQ49347.1 | apt | MED217_08076 | MED217_04372 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.634 |
EAQ49347.1 | guaA | MED217_08076 | MED217_10472 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.690 |
EAQ49347.1 | guaB | MED217_08076 | MED217_10517 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.639 |
EAQ49347.1 | nadD | MED217_08076 | MED217_00340 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.670 |
EAQ49347.1 | surE | MED217_08076 | MED217_03430 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.635 |
EAQ49347.1 | tdk | MED217_08076 | MED217_18676 | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | COG1435 Thymidine kinase. | 0.680 |
EAQ49348.1 | EAQ49347.1 | MED217_08081 | MED217_08076 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.980 |
EAQ49348.1 | EAQ49522.1 | MED217_08081 | MED217_11724 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Competence-damage inducible protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.692 |
EAQ49348.1 | EAQ51076.1 | MED217_08081 | MED217_16075 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.647 |
EAQ49348.1 | adk | MED217_08081 | MED217_03820 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.668 |
EAQ49348.1 | apt | MED217_08081 | MED217_04372 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.644 |
EAQ49348.1 | guaA | MED217_08081 | MED217_10472 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.690 |
EAQ49348.1 | guaB | MED217_08081 | MED217_10517 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.649 |
EAQ49348.1 | surE | MED217_08081 | MED217_03430 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.644 |
EAQ49348.1 | tdk | MED217_08081 | MED217_18676 | Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases. | COG1435 Thymidine kinase. | 0.639 |
EAQ49522.1 | EAQ49347.1 | MED217_11724 | MED217_08076 | Competence-damage inducible protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | Possible secreted 5'-nucleotidase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.692 |