| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ48021.1 | EAQ48334.1 | MED217_03355 | MED217_01010 | Hypothetical protein. | Hypothetical protein. | 0.738 |
| EAQ48021.1 | rlmH | MED217_03355 | MED217_11344 | Hypothetical protein. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.433 |
| EAQ48334.1 | EAQ48021.1 | MED217_01010 | MED217_03355 | Hypothetical protein. | Hypothetical protein. | 0.738 |
| EAQ48334.1 | rlmH | MED217_01010 | MED217_11344 | Hypothetical protein. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.450 |
| EAQ49339.1 | EAQ49445.1 | MED217_08036 | MED217_11339 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.500 |
| EAQ49339.1 | nadD | MED217_08036 | MED217_00340 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.700 |
| EAQ49339.1 | rlmH | MED217_08036 | MED217_11344 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.451 |
| EAQ49443.1 | EAQ49444.1 | MED217_11329 | MED217_11334 | COG4731 Uncharacterized protein conserved in bacteria. | COG1295 Predicted membrane protein. | 0.640 |
| EAQ49443.1 | EAQ49445.1 | MED217_11329 | MED217_11339 | COG4731 Uncharacterized protein conserved in bacteria. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.638 |
| EAQ49443.1 | rlmH | MED217_11329 | MED217_11344 | COG4731 Uncharacterized protein conserved in bacteria. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.462 |
| EAQ49444.1 | EAQ49443.1 | MED217_11334 | MED217_11329 | COG1295 Predicted membrane protein. | COG4731 Uncharacterized protein conserved in bacteria. | 0.640 |
| EAQ49444.1 | EAQ49445.1 | MED217_11334 | MED217_11339 | COG1295 Predicted membrane protein. | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.821 |
| EAQ49444.1 | rlmH | MED217_11334 | MED217_11344 | COG1295 Predicted membrane protein. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.630 |
| EAQ49445.1 | EAQ49339.1 | MED217_11339 | MED217_08036 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.500 |
| EAQ49445.1 | EAQ49443.1 | MED217_11339 | MED217_11329 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | COG4731 Uncharacterized protein conserved in bacteria. | 0.638 |
| EAQ49445.1 | EAQ49444.1 | MED217_11339 | MED217_11334 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | COG1295 Predicted membrane protein. | 0.821 |
| EAQ49445.1 | nadD | MED217_11339 | MED217_00340 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.953 |
| EAQ49445.1 | rlmH | MED217_11339 | MED217_11344 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.611 |
| EAQ49445.1 | rsfS | MED217_11339 | MED217_15335 | COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.439 |
| EAQ50250.1 | rlmH | MED217_04442 | MED217_11344 | COG2264 Ribosomal protein L11 methylase. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.479 |