STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ49674.1Hypothetical protein; COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit. (159 aa)    
Predicted Functional Partners:
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
       0.701
EAQ49673.1
ATP/GTP-binding site motif A (P-loop):ABC transporter; COG0419 ATPase involved in DNA repair.
       0.701
EAQ49671.1
GGDEF domain protein; COG3292 Predicted periplasmic ligand-binding sensor domain.
       0.472
EAQ49675.1
4-hydroxybenzoyl-CoA thioesterase domain protein; COG1607 Acyl-CoA hydrolase.
       0.461
Your Current Organism:
Leeuwenhoekiella blandensis
NCBI taxonomy Id: 398720
Other names: Flavobacterium sp. MED217, L. blandensis MED217, Leeuwenhoekiella blandensis MED217
Server load: low (24%) [HD]