node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAQ47790.1 | coaD-2 | MED217_08125 | MED217_13856 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.908 |
EAQ47790.1 | coaE | MED217_08125 | MED217_08155 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.784 |
EAQ47790.1 | coaX | MED217_08125 | MED217_03340 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.920 |
EAQ48927.1 | coaD-2 | MED217_10272 | MED217_13856 | COG3124 Uncharacterized protein conserved in bacteria. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.881 |
EAQ49013.1 | coaD-2 | MED217_10702 | MED217_13856 | Putative methyltransferase; COG0742 N6-adenine-specific methylase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.755 |
EAQ51315.1 | coaD-2 | MED217_17270 | MED217_13856 | Putative riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.771 |
EAQ51315.1 | coaE | MED217_17270 | MED217_08155 | Putative riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. | Putative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.509 |
EAQ51315.1 | guaA | MED217_17270 | MED217_10472 | Putative riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.445 |
EAQ51315.1 | nadD | MED217_17270 | MED217_00340 | Putative riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.507 |
EAQ51315.1 | pyrH | MED217_17270 | MED217_16610 | Putative riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.689 |
coaD-2 | EAQ47790.1 | MED217_13856 | MED217_08125 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.908 |
coaD-2 | EAQ48927.1 | MED217_13856 | MED217_10272 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | COG3124 Uncharacterized protein conserved in bacteria. | 0.881 |
coaD-2 | EAQ49013.1 | MED217_13856 | MED217_10702 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative methyltransferase; COG0742 N6-adenine-specific methylase. | 0.755 |
coaD-2 | EAQ51315.1 | MED217_13856 | MED217_17270 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. | 0.771 |
coaD-2 | coaE | MED217_13856 | MED217_08155 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.928 |
coaD-2 | coaX | MED217_13856 | MED217_03340 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative regulatory protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.926 |
coaD-2 | ddl | MED217_13856 | MED217_13861 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | D-alanylalanine synthetase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.781 |
coaD-2 | guaA | MED217_13856 | MED217_10472 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.740 |
coaD-2 | nadD | MED217_13856 | MED217_00340 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.638 |
coaD-2 | pyrH | MED217_13856 | MED217_16610 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.649 |