| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAQ48556.1 | EAQ48905.1 | MED217_08415 | MED217_10162 | Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.600 |
| EAQ48556.1 | EAQ51332.1 | MED217_08415 | MED217_17355 | Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II. | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.860 |
| EAQ48556.1 | EAQ51461.1 | MED217_08415 | MED217_18000 | Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II. | Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB. | 0.520 |
| EAQ48556.1 | polA | MED217_08415 | MED217_16690 | Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.980 |
| EAQ48570.1 | EAQ51332.1 | MED217_08485 | MED217_17355 | Signal peptidase I; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component; Belongs to the peptidase S26 family. | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.850 |
| EAQ48905.1 | EAQ48556.1 | MED217_10162 | MED217_08415 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II. | 0.600 |
| EAQ48905.1 | EAQ51332.1 | MED217_10162 | MED217_17355 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.999 |
| EAQ48905.1 | EAQ51412.1 | MED217_10162 | MED217_17755 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Exodeoxyribonuclease; COG0708 Exonuclease III. | 0.953 |
| EAQ48905.1 | EAQ51461.1 | MED217_10162 | MED217_18000 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB. | 0.999 |
| EAQ48905.1 | ligA | MED217_10162 | MED217_08061 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.541 |
| EAQ48905.1 | polA | MED217_10162 | MED217_16690 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
| EAQ51331.1 | EAQ51332.1 | MED217_17350 | MED217_17355 | Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.998 |
| EAQ51331.1 | EAQ51334.1 | MED217_17350 | MED217_17365 | Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. | Helicase domain protein; COG1201 Lhr-like helicases. | 0.881 |
| EAQ51331.1 | ligA | MED217_17350 | MED217_08061 | Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.456 |
| EAQ51331.1 | polA | MED217_17350 | MED217_16690 | Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. | Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.847 |
| EAQ51332.1 | EAQ48556.1 | MED217_17355 | MED217_08415 | DNA ligase; COG1793 ATP-dependent DNA ligase. | Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II. | 0.860 |
| EAQ51332.1 | EAQ48570.1 | MED217_17355 | MED217_08485 | DNA ligase; COG1793 ATP-dependent DNA ligase. | Signal peptidase I; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component; Belongs to the peptidase S26 family. | 0.850 |
| EAQ51332.1 | EAQ48905.1 | MED217_17355 | MED217_10162 | DNA ligase; COG1793 ATP-dependent DNA ligase. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.999 |
| EAQ51332.1 | EAQ51331.1 | MED217_17355 | MED217_17350 | DNA ligase; COG1793 ATP-dependent DNA ligase. | Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. | 0.998 |
| EAQ51332.1 | EAQ51334.1 | MED217_17355 | MED217_17365 | DNA ligase; COG1793 ATP-dependent DNA ligase. | Helicase domain protein; COG1201 Lhr-like helicases. | 0.880 |