STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAQ51332.1DNA ligase; COG1793 ATP-dependent DNA ligase. (536 aa)    
Predicted Functional Partners:
EAQ48905.1
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
   
 0.999
EAQ51331.1
Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.
 
 0.998
polA
Putative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.970
EAQ51461.1
Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
   
 0.920
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
     
 0.904
EAQ51412.1
Exodeoxyribonuclease; COG0708 Exonuclease III.
  
 
 0.899
EAQ51334.1
Helicase domain protein; COG1201 Lhr-like helicases.
 
    0.880
hisB
Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0241 Histidinol phosphatase and related phosphatases; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
   
 0.873
EAQ48556.1
Hypothetical protein; COG1061 DNA or RNA helicases of superfamily II.
   
 
 0.860
EAQ48570.1
Signal peptidase I; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component; Belongs to the peptidase S26 family.
    
 0.850
Your Current Organism:
Leeuwenhoekiella blandensis
NCBI taxonomy Id: 398720
Other names: Flavobacterium sp. MED217, L. blandensis MED217, Leeuwenhoekiella blandensis MED217
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