node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Glov_0237 | hemC | Glov_0237 | Glov_0502 | Conserved hypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.579 |
Glov_0501 | Glov_0504 | Glov_0501 | Glov_0504 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein; KEGG: gur:Gura_0361 cytochrome c assembly protein. | 0.957 |
Glov_0501 | Glov_0688 | Glov_0501 | Glov_0688 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.994 |
Glov_0501 | Glov_3417 | Glov_0501 | Glov_3417 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12; KEGG: gsu:GSU2996 precorrin-6y c5,15-methyltransferase. | 0.825 |
Glov_0501 | cobQ | Glov_0501 | Glov_3554 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.699 |
Glov_0501 | hemA | Glov_0501 | Glov_0503 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.986 |
Glov_0501 | hemC | Glov_0501 | Glov_0502 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
Glov_0501 | hemE | Glov_0501 | Glov_3245 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.967 |
Glov_0501 | hemH | Glov_0501 | Glov_2930 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.623 |
Glov_0501 | hemL | Glov_0501 | Glov_3139 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gme:Gmet_3356 glutamate-1-semialdehyde 2,1-aminomutase. | 0.872 |
Glov_0504 | Glov_0501 | Glov_0504 | Glov_0501 | TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein; KEGG: gur:Gura_0361 cytochrome c assembly protein. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.957 |
Glov_0504 | hemA | Glov_0504 | Glov_0503 | TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein; KEGG: gur:Gura_0361 cytochrome c assembly protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.884 |
Glov_0504 | hemC | Glov_0504 | Glov_0502 | TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein; KEGG: gur:Gura_0361 cytochrome c assembly protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.783 |
Glov_0504 | hemL | Glov_0504 | Glov_3139 | TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein; KEGG: gur:Gura_0361 cytochrome c assembly protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gme:Gmet_3356 glutamate-1-semialdehyde 2,1-aminomutase. | 0.426 |
Glov_0688 | Glov_0501 | Glov_0688 | Glov_0501 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.994 |
Glov_0688 | Glov_3417 | Glov_0688 | Glov_3417 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12; KEGG: gsu:GSU2996 precorrin-6y c5,15-methyltransferase. | 0.601 |
Glov_0688 | cobQ | Glov_0688 | Glov_3554 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.611 |
Glov_0688 | hemA | Glov_0688 | Glov_0503 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.878 |
Glov_0688 | hemC | Glov_0688 | Glov_0502 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
Glov_0688 | hemE | Glov_0688 | Glov_3245 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.762 |