STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Glov_2224KEGG: ppd:Ppro_2316 MiaB-like tRNA modifying enzyme; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB. (442 aa)    
Predicted Functional Partners:
Glov_2223
PFAM: protein of unknown function DUF748; KEGG: ppd:Ppro_2314 protein of unknown function DUF748.
       0.784
Glov_2225
PFAM: response regulator receiver; CheW domain protein; KEGG: ppd:Ppro_2364 response regulator receiver modulated CheW protein.
       0.769
Glov_3612
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.700
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.643
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
   0.580
Glov_2222
Ferritin Dps family protein; Iron-storage protein.
       0.532
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.484
Glov_1948
PFAM: PSP1 domain protein; KEGG: ppd:Ppro_1663 PSP1 domain protein.
  
     0.445
Glov_2219
KEGG: gsu:GSU1308 hypothetical protein.
     
 0.437
Glov_1228
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
  
 0.429
Your Current Organism:
Geobacter lovleyi
NCBI taxonomy Id: 398767
Other names: G. lovleyi SZ, Geobacter lovleyi SZ, Geobacter lovleyi str. SZ, Geobacter lovleyi strain SZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.