node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Glov_0501 | Glov_0688 | Glov_0501 | Glov_0688 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.994 |
Glov_0501 | hemA | Glov_0501 | Glov_0503 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.986 |
Glov_0501 | hemC | Glov_0501 | Glov_0502 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
Glov_0501 | hemE | Glov_0501 | Glov_3245 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.967 |
Glov_0501 | hemL | Glov_0501 | Glov_3139 | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gme:Gmet_3356 glutamate-1-semialdehyde 2,1-aminomutase. | 0.872 |
Glov_0688 | Glov_0501 | Glov_0688 | Glov_0501 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.994 |
Glov_0688 | Glov_1541 | Glov_0688 | Glov_1541 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | 0.450 |
Glov_0688 | hemA | Glov_0688 | Glov_0503 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.878 |
Glov_0688 | hemC | Glov_0688 | Glov_0502 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.996 |
Glov_0688 | hemE | Glov_0688 | Glov_3245 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.762 |
Glov_0688 | hemL | Glov_0688 | Glov_3139 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gme:Gmet_3356 glutamate-1-semialdehyde 2,1-aminomutase. | 0.994 |
Glov_1541 | Glov_0688 | Glov_1541 | Glov_0688 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gsu:GSU0135 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.450 |
Glov_1541 | Glov_2267 | Glov_1541 | Glov_2267 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | KEGG: gur:Gura_2012 erythronolide synthase; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Beta-ketoacyl synthase; Acyl transferase. | 0.964 |
Glov_1541 | hemC | Glov_1541 | Glov_0502 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.466 |
Glov_1541 | hemE | Glov_1541 | Glov_3245 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.460 |
Glov_1541 | hemL | Glov_1541 | Glov_3139 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gme:Gmet_3356 glutamate-1-semialdehyde 2,1-aminomutase. | 0.639 |
Glov_2267 | Glov_1541 | Glov_2267 | Glov_1541 | KEGG: gur:Gura_2012 erythronolide synthase; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Beta-ketoacyl synthase; Acyl transferase. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bpt:Bpet2311 putative polyketide synthase. | 0.964 |
Glov_2267 | hemL | Glov_2267 | Glov_3139 | KEGG: gur:Gura_2012 erythronolide synthase; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Beta-ketoacyl synthase; Acyl transferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gme:Gmet_3356 glutamate-1-semialdehyde 2,1-aminomutase. | 0.617 |
Glov_3140 | Glov_3141 | Glov_3140 | Glov_3141 | KEGG: ppd:Ppro_1509 hypothetical protein. | KEGG: gme:Gmet_3358 hypothetical protein. | 0.989 |
Glov_3140 | atpB | Glov_3140 | Glov_3142 | KEGG: ppd:Ppro_1509 hypothetical protein. | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.903 |