STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCOM_1595310Cyclin-dependent protein kinase, putative; Belongs to the cyclin family. (433 aa)    
Predicted Functional Partners:
RCOM_1454570
Transcription elongation factor SPT4 homolog; May regulate transcription elongation by RNA polymerase II. May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex; Belongs to the SPT4 family.
    
 0.900
RCOM_1432330
Cyclin h, putative; Belongs to the cyclin family.
     
 0.898
RCOM_0243690
Cak1, putative; Belongs to the protein kinase superfamily.
     
 0.897
RCOM_0855030
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
     
 0.843
RCOM_1400320
General transcription factor IIH subunit.
   
 
 0.832
RCOM_1406220
Pentatricopeptide repeat-containing protein, putative.
     
 0.831
RCOM_1406970
Cak assembly factor, putative.
     
 0.831
RCOM_0732490
Transcription elongation factor B polypeptide, putative; Belongs to the SKP1 family.
     
  0.829
RCOM_0267720
TFIIH basal transcription factor complex subunit, putative.
     
  0.829
RCOM_0936010
RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
     
 0.827
Your Current Organism:
Ricinus communis
NCBI taxonomy Id: 3988
Other names: R. communis, Ricinus communis L., Ricinus sanguineus, Ricinus sanguineus hort. ex Groenl., castor bean
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.