node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RCOM_0045870 | RCOM_0249880 | B9SSQ1 | B9T817 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ubiquitin-conjugating enzyme E2 I, putative; Belongs to the ubiquitin-conjugating enzyme family. | 0.888 |
RCOM_0045870 | RCOM_0720220 | B9SSQ1 | B9SK05 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA gyrase subunit A, chloroplast/mitochondrial, putative. | 0.837 |
RCOM_0045870 | RCOM_0720330 | B9SSQ1 | B9SK06 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA gyrase subunit A, chloroplast/mitochondrial, putative. | 0.837 |
RCOM_0045870 | RCOM_0731080 | B9SSQ1 | B9S374 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.636 |
RCOM_0045870 | RCOM_1447960 | B9SSQ1 | B9RH79 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.729 |
RCOM_0045870 | RCOM_1500700 | B9SSQ1 | B9R9U6 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Structural maintenance of chromosomes 6 smc6, putative. | 0.651 |
RCOM_0045870 | RCOM_1595270 | B9SSQ1 | B9R7Y4 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.729 |
RCOM_0100760 | RCOM_0388730 | B9T849 | B9TB48 | Structural maintenance of chromosomes protein. | Structural maintenance of chromosomes smc, bacterial, putative. | 0.997 |
RCOM_0100760 | RCOM_0720220 | B9T849 | B9SK05 | Structural maintenance of chromosomes protein. | DNA gyrase subunit A, chloroplast/mitochondrial, putative. | 0.717 |
RCOM_0100760 | RCOM_0720330 | B9T849 | B9SK06 | Structural maintenance of chromosomes protein. | DNA gyrase subunit A, chloroplast/mitochondrial, putative. | 0.717 |
RCOM_0100760 | RCOM_0731080 | B9T849 | B9S374 | Structural maintenance of chromosomes protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.634 |
RCOM_0100760 | RCOM_1447960 | B9T849 | B9RH79 | Structural maintenance of chromosomes protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.572 |
RCOM_0100760 | RCOM_1500520 | B9T849 | B9R9T8 | Structural maintenance of chromosomes protein. | Structural maintenance of chromosomes protein. | 0.997 |
RCOM_0100760 | RCOM_1500700 | B9T849 | B9R9U6 | Structural maintenance of chromosomes protein. | Structural maintenance of chromosomes 6 smc6, putative. | 0.801 |
RCOM_0100760 | RCOM_1595270 | B9T849 | B9R7Y4 | Structural maintenance of chromosomes protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.572 |
RCOM_0249880 | RCOM_0045870 | B9T817 | B9SSQ1 | Ubiquitin-conjugating enzyme E2 I, putative; Belongs to the ubiquitin-conjugating enzyme family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.888 |
RCOM_0249880 | RCOM_0720220 | B9T817 | B9SK05 | Ubiquitin-conjugating enzyme E2 I, putative; Belongs to the ubiquitin-conjugating enzyme family. | DNA gyrase subunit A, chloroplast/mitochondrial, putative. | 0.739 |
RCOM_0249880 | RCOM_0720330 | B9T817 | B9SK06 | Ubiquitin-conjugating enzyme E2 I, putative; Belongs to the ubiquitin-conjugating enzyme family. | DNA gyrase subunit A, chloroplast/mitochondrial, putative. | 0.739 |
RCOM_0249880 | RCOM_0731080 | B9T817 | B9S374 | Ubiquitin-conjugating enzyme E2 I, putative; Belongs to the ubiquitin-conjugating enzyme family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.975 |
RCOM_0249880 | RCOM_1500700 | B9T817 | B9R9U6 | Ubiquitin-conjugating enzyme E2 I, putative; Belongs to the ubiquitin-conjugating enzyme family. | Structural maintenance of chromosomes 6 smc6, putative. | 0.864 |