node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OAK51631.1 | OAK51632.1 | A3K89_11595 | A3K89_11590 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OAK51631.1 | OAK52452.1 | A3K89_11595 | A3K89_06370 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.419 |
OAK51631.1 | OAK52680.1 | A3K89_11595 | A3K89_07775 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.622 |
OAK51631.1 | OAK52681.1 | A3K89_11595 | A3K89_07780 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
OAK51631.1 | ilvC | A3K89_11595 | A3K89_07785 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.899 |
OAK51631.1 | leuB | A3K89_11595 | A3K89_07795 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.988 |
OAK51631.1 | leuC | A3K89_11595 | A3K89_07845 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.996 |
OAK51631.1 | leuD | A3K89_11595 | A3K89_07850 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.946 |
OAK51632.1 | OAK51631.1 | A3K89_11590 | A3K89_11595 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OAK51632.1 | OAK52452.1 | A3K89_11590 | A3K89_06370 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |
OAK51632.1 | OAK52680.1 | A3K89_11590 | A3K89_07775 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.813 |
OAK51632.1 | OAK52681.1 | A3K89_11590 | A3K89_07780 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
OAK51632.1 | OAK57438.1 | A3K89_11590 | A3K89_01150 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.412 |
OAK51632.1 | ilvC | A3K89_11590 | A3K89_07785 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.930 |
OAK51632.1 | leuB | A3K89_11590 | A3K89_07795 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.996 |
OAK51632.1 | leuC | A3K89_11590 | A3K89_07845 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.955 |
OAK51632.1 | leuD | A3K89_11590 | A3K89_07850 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.998 |
OAK52452.1 | OAK51631.1 | A3K89_06370 | A3K89_11595 | Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.419 |
OAK52452.1 | OAK51632.1 | A3K89_06370 | A3K89_11590 | Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |
OAK52452.1 | OAK52680.1 | A3K89_06370 | A3K89_07775 | Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |