STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OAK56887.1Heat-shock protein Hsp20; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. (147 aa)    
Predicted Functional Partners:
OAK51685.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
  
 
 0.767
OAK51533.1
Clp protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.767
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.767
OAK55918.1
NDP-hexose 4-ketoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
  
 
 0.767
OAK53181.1
Clp protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.767
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.750
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
  
  
 0.647
OAK54801.1
Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.616
OAK53949.1
Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.616
OAK56886.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.615
Your Current Organism:
Rhodococcus kyotonensis
NCBI taxonomy Id: 398843
Other names: CCTCC AB206088, IAM 15415, JCM 23211, R. kyotonensis, Rhodococcus kyotonensis Li et al. 2007, strain DS472
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.