STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OAK53154.1Thiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)    
Predicted Functional Partners:
OAK56633.1
Ribonucleotide-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.950
msrB
Peptide-methionine (R)-S-oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.738
OAK51230.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
  0.668
OAK54225.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.656
ribBA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.645
OAK56210.1
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.645
nrdI
Ribonucleotide reductase assembly protein NrdI; Probably involved in ribonucleotide reductase function.
  
  
 0.640
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.630
OAK56861.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.593
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.593
Your Current Organism:
Rhodococcus kyotonensis
NCBI taxonomy Id: 398843
Other names: CCTCC AB206088, IAM 15415, JCM 23211, R. kyotonensis, Rhodococcus kyotonensis Li et al. 2007, strain DS472
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