STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q0D566_ORYSJcDNA clone:J023073D03, full insert sequence. (454 aa)    
Predicted Functional Partners:
TK
Thymidine kinase.
    
  0.837
A3BMN8_ORYSJ
cDNA, clone: J080311G07, full insert sequence.
    
 0.827
A0A0P0Y4B5
Os11g0615250 protein.
    
 0.778
DRTS_ORYSJ
Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
    
 0.778
Q2R481_ORYSJ
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
    
 0.778
DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP, preventing uracil incorporation into DNA.
    
 0.746
Q5W6Y0_ORYSJ
cDNA clone:001-125-G09, full insert sequence; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
 0.746
Q67TV5_ORYSJ
cDNA clone:006-311-A10, full insert sequence.
     
 0.741
Q7XTF0_ORYSJ
Os04g0462300 protein.
     
 0.741
Q10LY9_ORYSJ
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative.
    
  0.716
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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