Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A0A0P0Y4B5 | DRTS_ORYSJ | A0A0P0Y4B5 | Q2QRX6 | Os11g0615250 protein. | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | 0.999 |
| A0A0P0Y4B5 | DUT | A0A0P0Y4B5 | Q10FF9 | Os11g0615250 protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP, preventing uracil incorporation into DNA. | 0.984 |
| A0A0P0Y4B5 | HAL3 | A0A0P0Y4B5 | Q69K55 | Os11g0615250 protein. | Phosphopantothenoylcysteine decarboxylase; Catalyzes the decarboxylation of 4'- phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis. Involved in salt and osmotic tolerance, and light-regulated plant growth. Trimerization of HAL3 recruits and activates the E3 ubiquitin-protein ligase HIP1, which leads to the degradation of cell cycle suppressors, resulting in enhancement of cell division and plant growth. HAL3 function in cell division seems to be independent from its PPC decarboxylase activity. Belongs to the HFCD (homooligomeric flavin containin [...] | 0.973 |
| A0A0P0Y4B5 | OJ1112_E07.4 | A0A0P0Y4B5 | Q0J035 | Os11g0615250 protein. | 4'-phosphopantetheine phosphatase; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration. Functionally redudant with PANK1 (By similarity). The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'-phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre- empts damage in the CoA pathway (By similarity). Hydrolyzing excess 4'- phosphopantetheine could constitute a directed overflow mechanism to preve [...] | 0.801 |
| A0A0P0Y4B5 | OJ1134_B10.16 | A0A0P0Y4B5 | Q0J7N5 | Os11g0615250 protein. | Phosphopantothenate--cysteine ligase 2; Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine; Belongs to the PPC synthetase family. | 0.956 |
| A0A0P0Y4B5 | P0460H02.10 | A0A0P0Y4B5 | Q94DR2 | Os11g0615250 protein. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A. | 0.846 |
| A0A0P0Y4B5 | P0529B09.16 | A0A0P0Y4B5 | Q69TF4 | Os11g0615250 protein. | Pantothenate kinase 1; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration (By similarity); Belongs to the type II pantothenate kinase family. | 0.801 |
| A0A0P0Y4B5 | PANC | A0A0P0Y4B5 | O24210 | Os11g0615250 protein. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine to form pantothenate. Essential for panthotenate biosynthesis (Probable). | 0.499 |
| A0A0P0Y4B5 | Q2R481_ORYSJ | A0A0P0Y4B5 | Q2R481 | Os11g0615250 protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
| A0A0P0Y4B5 | Q5W6Y0_ORYSJ | A0A0P0Y4B5 | Q5W6Y0 | Os11g0615250 protein. | cDNA clone:001-125-G09, full insert sequence; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.984 |
| DRTS_ORYSJ | A0A0P0Y4B5 | Q2QRX6 | A0A0P0Y4B5 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Os11g0615250 protein. | 0.999 |
| DRTS_ORYSJ | DUT | Q2QRX6 | Q10FF9 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP, preventing uracil incorporation into DNA. | 0.984 |
| DRTS_ORYSJ | HAL3 | Q2QRX6 | Q69K55 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Phosphopantothenoylcysteine decarboxylase; Catalyzes the decarboxylation of 4'- phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis. Involved in salt and osmotic tolerance, and light-regulated plant growth. Trimerization of HAL3 recruits and activates the E3 ubiquitin-protein ligase HIP1, which leads to the degradation of cell cycle suppressors, resulting in enhancement of cell division and plant growth. HAL3 function in cell division seems to be independent from its PPC decarboxylase activity. Belongs to the HFCD (homooligomeric flavin containin [...] | 0.973 |
| DRTS_ORYSJ | OJ1112_E07.4 | Q2QRX6 | Q0J035 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | 4'-phosphopantetheine phosphatase; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration. Functionally redudant with PANK1 (By similarity). The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'-phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre- empts damage in the CoA pathway (By similarity). Hydrolyzing excess 4'- phosphopantetheine could constitute a directed overflow mechanism to preve [...] | 0.801 |
| DRTS_ORYSJ | OJ1134_B10.16 | Q2QRX6 | Q0J7N5 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Phosphopantothenate--cysteine ligase 2; Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine; Belongs to the PPC synthetase family. | 0.956 |
| DRTS_ORYSJ | P0460H02.10 | Q2QRX6 | Q94DR2 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A. | 0.846 |
| DRTS_ORYSJ | P0529B09.16 | Q2QRX6 | Q69TF4 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Pantothenate kinase 1; Catalyzes the phosphorylation of pantothenate the first step in CoA biosynthesis. May play a role in the physiological regulation of the intracellular CoA concentration (By similarity); Belongs to the type II pantothenate kinase family. | 0.801 |
| DRTS_ORYSJ | PANC | Q2QRX6 | O24210 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine to form pantothenate. Essential for panthotenate biosynthesis (Probable). | 0.585 |
| DRTS_ORYSJ | Q2R481_ORYSJ | Q2QRX6 | Q2R481 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
| DRTS_ORYSJ | Q5W6Y0_ORYSJ | Q2QRX6 | Q5W6Y0 | Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). | cDNA clone:001-125-G09, full insert sequence; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.984 |
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