STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CYP93G1Cytochrome P450 93G1; Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones. In vitro, can desaturate naringenin and eriodictyol to apigenin and luteolin, respectively. Acts as a key branch point enzyme that channels flavanones to the biosynthesis of tricin O-linked conjugates. (516 aa)    
Predicted Functional Partners:
A0A0P0V5N7
Os01g0633500 protein.
   
 0.962
F3H-1
Flavanone 3-dioxygenase 1; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. Converts (2S)-eriodictyol to (+)-taxifolin and (2S)-naringenin to (+)- (2R/3R)-dihydrokaempferol in vitro.
   
 0.959
CHI
Chalcone--flavonone isomerase; Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
   
 
 0.954
CYP75B3
Flavonoid 3'-monooxygenase CYP75B3; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes the 3'- hydroxylation of apigenin to generate luteolin (Probable). Belongs to the cytochrome P450 family.
  
  
0.948
CYP75B4
Flavonoid 3'-monooxygenase CYP75B4; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Catalyzes in vitro 3'-hydroxylation of different flavonoids. Catalyzes the conversion of apigenin to luteolin, naringenin to eriodictyol, and kaempferol to quercetin. Possesses specific 5'-hydroxylase activity toward chrysoeriol (a 3'-methoxylated flavone) and is indispensable for tricin formation. Converts chrysoeriol to selgin, a precursor of tricin, suggesting that chrysoeriol, instead of tricetin, is an intermediate in tricin biosynthesis.
  
  
0.948
Q2QYK6_ORYSJ
Chalcone-flavonone isomerase family protein; Belongs to the chalcone isomerase family.
     
 0.907
Q2RBC7_ORYSJ
Chalcone-flavonone isomerase family protein; Belongs to the chalcone isomerase family.
     
 0.904
APR1
Probable 5'-adenylylsulfate reductase 1, chloroplastic; Reduces sulfate for Cys biosynthesis.
    
 0.873
NOMT_ORYSJ
Naringenin 7-O-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase involved in the biosynthesis of the sakuranetin, an inducible defense mechanism of O.sativa against pathogen attack; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
     
 0.864
A0A0P0VYL2
Os03g0367101 protein.
     
0.851
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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