STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BZIP46bZIP transcription factor 46; Transcription factor involved in abscisic acid (ABA) signaling pathway. Transcription factor activity is fully activated by ABA. Acts as positive regulator of the expression of abiotic stress-responsive genes through an ABA-dependent signaling pathway. Acts as positive regulator of ABA signaling and drought stress tolerance. Plays an important role in ABA and auxin responses. Involved in ABA signaling and stress responses by directly binding to the ABA-responsive element (ABRE)-containing genes, especially WRKY family genes. Modulates response to auxin. Su [...] (324 aa)    
Predicted Functional Partners:
SAPK6
Serine/threonine-protein kinase SAPK6; May play a role in signal transduction of hyperosmotic response (Probable). Can phosphorylate ABI5 in vitro. Can phosphorylate BZIP46 in vitro. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
 0.922
SAPK10
Serine/threonine-protein kinase SAPK10; May play a role in signal transduction of hyperosmotic response. Together with PYL10, PP2C53 and SAPK8, may form an abscisic acid (ABA) signaling module involved in stress response. Together with PYL3 and PP2C50, may form an ABA signaling module involved in stress response.
   
 0.915
SAPK9
Serine/threonine-protein kinase SAPK9; May play a role in signal transduction of hyperosmotic response (Probable). Can phosphorylate BZIP46 in vitro.
   
 0.913
SAPK2
Serine/threonine-protein kinase SAPK2; May play a role in signal transduction of hyperosmotic response (Probable). Can phosphorylate BZIP46 in vitro. Together with ABI5, PP2C30 and PYL5, is part of an abscisic acid (ABA) signaling unit that modulates seed germination and early seedling growth ; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
 0.887
SAPK4
Serine/threonine-protein kinase SAPK4; May play a role in signal transduction of hyperosmotic response.
   
 0.879
SAPK1
Serine/threonine-protein kinase SAPK1; May play a role in signal transduction of hyperosmotic response; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
 0.875
SAPK3
Serine/threonine-protein kinase SAPK3; May play a role in signal transduction of hyperosmotic response; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
 0.864
SAPK7
Serine/threonine-protein kinase SAPK7; May play a role in signal transduction of hyperosmotic response; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
   
 0.859
A0A0P0WMT0
Os05g0433100 protein.
   
  0.846
MODD
Ninja-family protein MODD; Acts as negative regulator of abscisic acid (ABA) signaling and drought tolerance. Mediates deactivation and degradation of BZIP46, a positive regulator of ABA signaling and drought stress tolerance. Represses BZIP46 activity via interaction with the TPR3-HDAC1 corepressor complex and down-regulation of the histone acetylation level at BZIP46 target genes. Promotes BZIP46 degradation via interaction with the U-box type ubiquitin E3 ligase PUB70.
    
 
 0.811
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.