STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q75HP7_ORYSJSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (587 aa)    
Predicted Functional Partners:
Q6ZKK5_ORYSJ
cDNA clone:J033107D20, full insert sequence.
  
 0.995
A0A0P0V7A3
Os01g0711400 protein.
  
 
 0.986
A0A0P0WYK7
Os06g0611900 protein.
  
 
 0.986
Q7XPR2_ORYSJ
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.985
Q0J1E1_ORYSJ
Os09g0446800 protein.
  
 0.983
Q10T42_ORYSJ
(RAP Annotation release2) Formyltetrahydrofolate deformylase family protein.
  
 0.976
Q6ZFI6_ORYSJ
cDNA clone:J013000A23, full insert sequence.
  
 0.971
MTHR_ORYSJ
Probable methylenetetrahydrofolate reductase; The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10- methylenetetrahydrofolate to serine, sugars and starch.
  
 
 0.970
URED
Urease accessory protein D; Required for the maturation and activation of urease via the functional incorporation of the urease nickel metallocenter. Belongs to the UreD family.
  
 0.969
DRTS_ORYSJ
Putative bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
  
 
 0.969
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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