STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7XPZ2_ORYSJcDNA clone:J033122C24, full insert sequence. (629 aa)    
Predicted Functional Partners:
P0535F09.39
Serine/threonine-protein kinase ATR; Probable serine/threonine kinase. Seems to play a central role in cell-cycle regulation by transmitting DNA damage signals to downstream effectors of cell-cycle progression. May recognize the substrate consensus sequence [ST]-Q and phosphorylate histone variant H2AX to form H2AXS139ph at sites of DNA damage, thereby regulating DNA damage response mechanism (By similarity); Belongs to the PI3/PI4-kinase family. ATM subfamily.
   
 0.972
Q5VND0_ORYSJ
cDNA clone:J023002O16, full insert sequence.
    
 0.965
Q0JQF8_ORYSJ
Os01g0164900 protein.
   
 0.953
Q0JQF9_ORYSJ
Os01g0164800 protein.
   
 0.953
NBS1
Nijmegen breakage syndrome 1 protein; Component of the MRE11-RAD50-NBN complex (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex may be involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, and cell cycle checkpoint control. Functions also in the very early stages of meiosis.
    
 0.951
RTEL1
Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA replication, DNA repair and the maintenance of genomic stability. Acts as an anti- recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.
   
 0.941
A0A0P0WNT7
Os05g0486600 protein.
  
  
 
0.941
A0A0P0XQZ3
Os09g0551800 protein.
   
 0.941
A0A0P0Y424
Os11g0586100 protein.
   
 0.929
A0A0P0UX66
Os01g0106700 protein; Belongs to the PI3/PI4-kinase family.
    
 0.926
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.