STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD1Two-component response regulator ORR30; Transcriptional activator that acts as floral inducer to promote short-day (SD) flowering pathway. Activates HD3A and other FT- like genes independently from HD1. May also activate MADS-box transcription factors involved in flowering regulation. Functions as a response regulator involved in His- to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. May directly activate some type-A response regulators in response [...] (341 aa)    
Predicted Functional Partners:
HD5
Nuclear transcription factor Y subunit B-11; Probable transcription factor involved in the regulation of flowering time under long day (LD) conditions. Functions as repressor of flowering, independently of HD1 and GHD7. Controls flowering time by negatively regulating the expression of EHD1 and HD3A. Regulates plant height by promoting cell elongation in the internodes. Component of the NF-Y/HAP transcription factor complex (By similarity); Belongs to the NFYB/HAP3 subunit family.
    
 
 0.666
EHD2
Protein EARLY HEADING DATE 2; Transcription activator that acts as a flowering master switch in both long and short days, independently of the circadian clock. Promotes flowering upstream of HD1 by up-regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1. Seems to repress FTL11 expression. May recognize the consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters.
    
 0.648
EHD3
PHD finger protein EHD3; Probable transcription factor involved in the regulation of floral induction under long day (LD) conditions. Promotes photoperiodic flowering by repressing GHD7, a major floral repressor. Seems to function independently of HD1.
     
 0.628
C7J0W5_ORYSJ
Os04g0429200 protein; Belongs to the peptidase C19 family.
    
  0.614
GHD7
Transcription factor GHD7; Probable transcription factor involved in the regulation of flowering time under long day (LD) conditions. Plays a major role as repressor of flowering. Controls flowering time by negatively regulating the expression of EHD1 and HD3A.
      
 0.613
RFT1
Protein RICE FLOWERING LOCUS T 1; Probable mobile flower-promoting signal (florigen) that moves from the leaf to the shoot apical meristem (SAM) and induces flowering. Promotes the transition from vegetative growth to flowering under long day (LD) conditions. Acts upstream of MADS14 and MADS15. May also participate in the promotion of flowering under short day (SD) conditions.
      
 0.613
HD3A
Protein HEADING DATE 3A; Probable mobile flower-promoting signal (florigen) that moves from the leaf to the shoot apical meristem (SAM) and induces flowering. Promotes the transition from vegetative growth to flowering downstream of HD1 and EHD1 under short day (SD) conditions. Acts upstream of MADS14 and MADS15. Belongs to the phosphatidylethanolamine-binding protein family.
      
 0.613
HD1
Zinc finger protein HD1; Probable transcription factor involved in the regulation of flower development. Required for the promotion of flowering under short day (SD) conditions and the suppression of flowering under long day (LD) conditions. Regulates positively the floral activator HEADING DATE 3a (HD3A) under SD and negatively under LD conditions. Belongs to the CONSTANS family.
      
 0.613
GCN5
Histone acetyltransferase GCN5; Acetylates histone H3. Acetylation of histones gives a specific tag for epigenetic transcription activation. Operates in concert with certain DNA-binding transcriptional activators. Acts via the formation of large multiprotein complexes that modify the chromatin (By similarity).
    
  0.582
Q84SZ4_ORYSJ
cDNA clone:J013132N21, full insert sequence.
    
  0.582
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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