STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMA3Cadmium/zinc-transporting ATPase HMA3; Root-specific cadmium (Cd) transporter that mediates Cd efflux in root vacuoles. Involved in Cd detoxification by sequestrating Cd into root vacuoles and limiting translocation of Cd from the roots to the shoots, and accumulation in grains. (1004 aa)    
Predicted Functional Partners:
CCS
Copper chaperone for superoxide dismutase, chloroplastic; Copper chaperone for superoxide dismutases (SODs). Binds copper ions and delivers them specifically to SODs. Is required for assistance in SODs disulfide bond formation and thereby activation of SODs (By similarity).
  
 0.969
MTP1
Metal tolerance protein 1; Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
  
  
 0.690
A0A0P0V1T6
Os01g0314700 protein.
    
 0.682
NRAMP1
Metal transporter Nramp1; Probable metal transporter that may participate in the control of iron homeostasis; Belongs to the NRAMP (TC 2.A.55) family.
  
 
 0.674
NRAMP2
Metal transporter Nramp2; Probable metal transporter; Belongs to the NRAMP (TC 2.A.55) family.
  
 
 0.592
Q75J02_ORYSJ
Os03g0412300 protein.
    
 0.589
IRT1
Fe(2+) transport protein 1; Iron transporter involved in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer. May also transport other divalent cations.
      
 0.588
LAC23
Laccase-23; Lignin degradation and detoxification of lignin-derived products; Belongs to the multicopper oxidase family.
  
 
 0.581
Q5JL91_ORYSJ
cDNA clone:J023077M05, full insert sequence.
    
 0.570
Q6I5G4_ORYSJ
Os05g0534500 protein.
    
 0.570
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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