STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRAMP5Metal transporter Nramp5; Probable metal transporter; Belongs to the NRAMP (TC 2.A.55) family. (538 aa)    
Predicted Functional Partners:
HMA3
Cadmium/zinc-transporting ATPase HMA3; Root-specific cadmium (Cd) transporter that mediates Cd efflux in root vacuoles. Involved in Cd detoxification by sequestrating Cd into root vacuoles and limiting translocation of Cd from the roots to the shoots, and accumulation in grains.
  
 
 0.542
BHLH156
Transcription factor BHLH156; Transcription factor involved in positive regulation of genes involved in strategy II iron acquisition, including genes for mugineic acid (MA) family phytosiderophores biosynthesis, and genes involved in S-adenosylmethionine cycle and iron transport. May play a role in the regulation of iron deficiency response by promoting the nuclear localization of IRO2. Possesses transactivation activity in yeast. Belongs to the bHLH protein family.
   
  
 0.488
HMA4
Copper-transporting ATPase HMA4; Copper (Cu) transporter that mediates Cu transport in root vacuoles. Involved in Cu detoxification by sequestrating Cu into root vacuoles and limiting translocation of Cu from the roots to the shoots, and accumulation in grains.
  
 
 0.486
HMA2
Cadmium/zinc-transporting ATPase HMA2; Zinc/cadmium transporter that plays an essential role in promoting translocation of zinc and cadmium from roots to shoots. May control cadmium loading into xylem. In roots, transports zinc and cadmium from the apoplast to the symplast to facilitate translocation via the phloem. In nodes, functions to load zinc and cadmium to the phloem for the preferential distribution to the upper nodes and panicles. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
  
 
 0.453
A3C052_ORYSJ
cDNA clone:J013047J08, full insert sequence.
     
 0.451
Q6YVT1_ORYSJ
cDNA clone:J023115E06, full insert sequence.
     
 0.451
IRT1
Fe(2+) transport protein 1; Iron transporter involved in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer. May also transport other divalent cations.
      
 0.434
atpH
ATP synthase subunit c, chloroplastic; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
    
  0.426
Q0IPT8_ORYSJ
V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
    
  0.426
VATP-P1
V-type proton ATPase 16 kDa proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
    
  0.426
Your Current Organism:
Oryza sativa Japonica
NCBI taxonomy Id: 39947
Other names: Japanese rice, Japonica rice, O. sativa Japonica Group, Oryza sativa (japonica cultivar-group), Oryza sativa Japonica Group, Oryza sativa subsp. japonica
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