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radA protein (Metallosphaera sedula) - STRING interaction network
"radA" - DNA repair and recombination protein RadA in Metallosphaera sedula
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (324 aa)    
Predicted Functional Partners:
Msed_0010
PFAM- histidine triad (HIT) protein (169 aa)
   
        0.912
rfcS
Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (326 aa)
 
 
  0.860
secY
Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (463 aa)
 
     
  0.856
Msed_0011
L-threonine ammonia-lyase; TIGRFAM- threonine dehydratase; PFAM- Pyridoxal-5’-phosphate-dependent enzyme, beta subunit (402 aa)
     
 
  0.848
top6A
Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family (386 aa)
   
 
  0.845
Msed_0007
TIGRFAM- putative RNA methylase, NOL1/NOP2/sun family; PFAM- Fmu (Sun) domain protein (336 aa)
   
   
  0.837
hjc
Holliday junction resolvase Hjc; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5’-terminal phosphate and a 3’-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family (144 aa)
         
  0.837
priS
DNA primase small subunit PriS; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...] (320 aa)
     
 
  0.834
Msed_0008
annotation not available (156 aa)
   
   
  0.827
Msed_0760
PFAM- protein of unknown function DUF87 (492 aa)
         
  0.819
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula, Metallosphaera sedula DSM 5348, Metallosphaera sedula DSM5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
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