STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msed_0063PFAM: protein of unknown function DUF655. (211 aa)    
Predicted Functional Partners:
Msed_0064
PFAM: ribosomal RNA adenine methylase transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
     
 0.950
Msed_0065
TIGRFAM: putative methylase; PFAM: methyltransferase small.
 
     0.947
Msed_0066
PFAM: tRNA/rRNA methyltransferase (SpoU).
 
     0.947
rpl21e
PFAM: ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
  
 0.939
rps3ae
PFAM: ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.921
Msed_0068
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase.
 
     0.859
Msed_0062
DNA-directed RNA polymerase, subunit F; PFAM: RNA polymerase Rpb4.
     
 0.844
dnaG
TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.750
rpl18e
PFAM: ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL18 family.
 
     0.738
spt5
LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.721
Your Current Organism:
Metallosphaera sedula
NCBI taxonomy Id: 399549
Other names: M. sedula DSM 5348, Metallosphaera sedula DSM 5348, Metallosphaera sedula IFO 15509, Metallosphaera sedula JCM 9185, Metallosphaera sedula NBRC 15509, Metallosphaera sedula str. DSM 5348, Metallosphaera sedula strain DSM 5348
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.